Polycystic Ovarian Syndrome (PCOS) is the most ordinary endocrine-related dysfunction in women of reproductive age. Multiple studies have observed a better prevalence of psychiatric illness, including depressive disorders, anxiety disorders, and manic depression in women with PCOS, the character of this association isn't fully understood. Some studies have hypothesized that the hormonal dysregulation seen in women with PCOS may increase vulnerability to mental health disorders.
Other studies have questioned whether the medications won't treat mental disorders. Specifically, mood stabilizers may increase the risk of PCOS. A recent study has checked out the temporal association between PCOS and psychiatric illness to assist in distinguishing these two possibilities.
Women with PCOS who used metformin for treatment showed a significantly reduced risk of developing manic depression compared to non-users. PCOS patients treated with hormone therapy also showed a lower risk of developing manic depression compared to non-users; however, the reduction in risk wasn't as substantial as seen with metformin and wasn't statistically significant.
One of the first exciting findings is that in women with PCOS, treatment with metformin seems to decrease the danger of developing manic depression. Hormonal therapy demonstrated a less robust reduction in risk, which wasn't statistically significant. Metformin is an oral hypoglycaemic agent that corrects glucose resistance in women with PCOS; metformin also has direct anti-inflammatory effects, which the authors suggest may contribute to decreasing risk for manic depression.
Many women with PCOS, especially when it's relatively mild, aren't aware that they need PCOS. Some women have mild symptoms and don't receive any specific treatment. The approach varies, and interventions for more severe symptoms include dietary modifications, oral contraceptives, progestins, spironolactone, and metformin. Although this study must be replicated in other populations, the finding that metformin may reduce the danger of manic depression in women with PCOS argues for considering using this medication more widely.
Effects of PCOD
The side effects of PCOD include:
Insulin Resistance results in High Testosterone:
In women with PCOS, insulin resistance is usually a red flag that you may have existing diabetes or are in danger for diabetes—as well as for those without polycystic ovary syndrome. Insulin resistance means your body is a smaller amount ready to send enough glucose to the cells needing fuel throughout your body. The pancreas produces more insulin when this happens to assist in keeping glucose levels even. The additional insulin may have several adverse effects, including shutting down your ovaries and resulting in above-average levels of male hormones, called androgens, including testosterone.
Hormone Imbalances Impose Negative impacts on Your Whole Body:
Irregular menstrual cycles:
Most girls with PCOS have unpredictable menstrual cycles with infrequent periods (often quite 35 days apart) or no periods in the least (amenorrhea). One of the main rationales for your irregular ovulation or no menstruation may be a direct effect of hormone imbalances. Your periods could also be light because you're not ovulating or extremely heavy. After all, the liner of your uterus, called the endometrium, continues to thicken when the monthly cycle doesn't happen.
Infertility:
With PCOS, hormonal imbalances interfere with regular ovulation. When your ovaries don't release an egg, you can't conceive. Polycystic ovary syndrome (PCOS) is the leading cause for infertility in women, consistent with the American College of Obstetricians and Gynecologists.
Common Symptoms of PCOS
Weight gain:
Approximately, it is found that 80% of girls with PCOS gain weight. When the body attempts to store more fat that is healthy – especially in your midsection (abdominal fat), it may further raise your risk for serious chronic diseases like diabetes, disorder, and even endometrial carcinoma. While weight gain doesn't cause PCOD, it can make it harder to manage your weight, but it's helpful to understand that by losing just 2-10% of your excess body fat (which is usually only 5-10 lbs for several women).
Excessive hair growth or hair loss:
About 70% of girls with PCOS develop so-called "male-pattern" hair growth on the upper lip, chin, and neck, sides of the face, abdomen, lower back, upper arms, and inner thighs. Some women even have "male-pattern" hair by thinning of the scalp and top of the top. The explanation for these hair changes is attributed to high androgen levels stimulating hair follicles.
Adult acne:
High levels of male hormones that occur in women with PCOD can also cause severe acne on your face, back, and chest, – particularly in women who are past their teen years. The primary cause can be attributed break-outs, and clogged pores might not clearing up with conventional acne treatments from the pharmacy or of your general practitioner or dermatologist.